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Meg Ryan has published a heartfelt tribute to the late filmmaker Rob Reiner, who was her director in the hit romantic comedy When Harry Met Sally.

A Devastating Incident

Reiner was discovered deceased alongside his spouse, Michele Singer Reiner, at their residence in LA over the weekend.

“We will miss this man so deeply…” the actress posted on Instagram, alongside a picture of them together. “Our gratitude, Rob and Michele, for your faith in true love, stories, and joy. Your trust in people's goodness and your love for this nation are remembered.”

Charges Filed

Reiner’s son Nick, 32, has been charged with two counts of first-degree murder and was in court today. He’s being incarcerated with no bail set. It’s been reported that Reiner’s daughter Romy discovered her father deceased.

“It is my belief that from this horror, positive change and understanding can emerge,” Ryan added. “I don’t know, but my guess is that they would want that to be hopeful and humane, to be something that brings us all to a greater understanding of one another and to some peace.”

Children Share Their Grief

Reiner’s surviving children Jake and Romy issued words today. “No words can convey the constant, profound sorrow we feel,” they said. “The horrific and devastating loss of our parents, Rob and Michele Reiner, is something that no one should ever experience. They were more than parents; they were our closest confidants.”

Hollywood Tributes Pour In

Ryan’s co-star, Billy Crystal, similarly honored Reiner via comments shared yesterday together with remarks by Larry David, Martin Short and Albert Brooks.

“His comedic touch was beyond compare, his love of getting the music of the dialogue just right, and his sharpening of the edge of a drama was simply elegant,” it read. “For the actors, he loved them. For the writers he made them better. Freedom was his key offering. He listened to ideas and included you in the creative journey. Everyone felt like part of a crew. His direction was a gift, but his legacy is broader.”

An Enduring Filmography

When Harry Met Sally was a box office and critical triumph in 1989, making over $93m at the box office and scoring Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner was introduced to Michele Singer Reiner whilst filming When Harry Met Sally. The pair were connected through Barry Sonnenfeld, a fellow filmmaker and pal.

Reiner’s extensive filmography also included classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were married for 36 years.